Kaiba from Yu-Gi-Oh! and Zuckerberg from The Social Network both share unyielding dedication to their respective businesses. Kaiba inherits his corporation from Gozaburo Kaiba, his stepfather. Mark built Facebook himself.
What makes these two so intensely focused on their business missions? Pain drives each. Kaiba wants to bury the past. Mark wants to get over his inconsiderate treatment of Erica Albright.
Overcoming the trauma of pain through company-building is what unites the characters Kaiba, and Mark as played by Jesse Eisenberg.